Lei Xi Selected Research

visnagin

2/2016	Visnagin-a new protectant against doxorubicin cardiotoxicity? Inhibition of mitochondrial malate dehydrogenase 2 (MDH2) and beyond.
1/2016	Potential Therapeutic Strategies for Hypertension-Exacerbated Cardiotoxicity of Anticancer Drugs.

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Lei Xi Research Topics

Disease

38	Neoplasms (Cancer) 01/2022 - 09/2010
21	Ischemia 07/2022 - 07/2002
13	Reperfusion Injury 02/2014 - 02/2004
12	Infarction (Infarctions) 04/2022 - 07/2002
12	Hypoxia (Hypoxemia) 12/2020 - 12/2004
9	Breast Neoplasms (Breast Cancer) 01/2021 - 05/2013
9	Myocardial Infarction 09/2020 - 01/2006
9	Cardiotoxicity 01/2020 - 09/2010
8	Necrosis 11/2018 - 04/2005
7	Erectile Dysfunction 03/2015 - 04/2003
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 08/2017
6	Myocardial Ischemia (Ischemic Heart Diseases) 06/2015 - 10/2008
5	Alzheimer Disease (Alzheimer's Disease) 10/2019 - 09/2013
5	Cardiomyopathies (Cardiomyopathy) 05/2012 - 09/2010
4	Glaucoma 01/2020 - 01/2014
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 01/2011
3	Lung Neoplasms (Lung Cancer) 11/2021 - 09/2010
3	Inflammation (Inflammations) 01/2021 - 09/2018
3	Fibrosis (Cirrhosis) 09/2020 - 10/2014
3	Pulmonary Arterial Hypertension 01/2019 - 04/2005
3	Heart Failure 08/2018 - 01/2009
3	Atrial Fibrillation 01/2014 - 01/2011
3	Pulmonary Hypertension 01/2011 - 02/2004
2	Cognitive Dysfunction 03/2022 - 10/2019
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 04/2016
2	Prostatic Neoplasms (Prostate Cancer) 11/2020 - 01/2020
2	Body Weight (Weight, Body) 08/2020 - 02/2014
2	Myopia 02/2020 - 08/2018
2	Astigmatism 02/2020 - 05/2018
2	Hypothermia 01/2020 - 12/2008
2	Hyperoxia 10/2019 - 08/2015
2	Prediabetic State (Prediabetes) 03/2019 - 01/2017
2	Neoplasm Metastasis (Metastasis) 01/2019 - 04/2016
2	Type 2 Diabetes Mellitus (MODY) 01/2017 - 02/2014
2	Cardiomegaly (Heart Hypertrophy) 03/2015 - 01/2011
2	Blister (Bulla) 10/2014 - 01/2014
2	Brain Ischemia (Cerebral Ischemia) 05/2013 - 06/2012
2	Ventricular Dysfunction 05/2011 - 01/2006

Drug/Important Bio-Agent (IBA)

13	Sildenafil Citrate (Viagra)FDA Link 11/2020 - 04/2003
11	Pharmaceutical PreparationsIBA 07/2022 - 04/2003
11	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 11/2020 - 04/2005
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2011
8	Phosphodiesterase 5 InhibitorsIBA 11/2020 - 04/2005
8	Tadalafil (Cialis)FDA Link 05/2020 - 02/2004
7	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2011
7	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2019 - 09/2010
6	NitratesIBA 05/2020 - 05/2011
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2022 - 10/2006
4	Therapeutic UsesIBA 03/2022 - 01/2011
4	PolymersIBA 01/2021 - 12/2019
4	Hemoglobins (Hemoglobin)IBA 01/2021 - 08/2015
4	Glucose (Dextrose)FDA LinkGeneric 05/2020 - 02/2014
4	Small Interfering RNA (siRNA)IBA 01/2017 - 10/2005
4	Vardenafil Dihydrochloride (Levitra)FDA Link 03/2015 - 02/2004
3	Contrast MediaIBA 01/2021 - 03/2013
3	LigandsIBA 01/2021 - 01/2006
3	HypoxanthineIBA 06/2020 - 01/2011
3	NitritesIBA 05/2020 - 05/2011
3	Sirtuin 1IBA 12/2019 - 01/2014
3	Insulin (Novolin)FDA Link 03/2019 - 02/2014
3	Messenger RNA (mRNA)IBA 03/2019 - 06/2012
3	InterleukinsIBA 01/2019 - 01/2013
3	Adenosine Triphosphate (ATP)IBA 01/2017 - 04/2003
3	OsteoprotegerinIBA 01/2014 - 01/2011
3	RANK LigandIBA 01/2014 - 01/2011
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 09/2010 - 07/2002
3	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2008 - 02/2004
2	Bevacizumab (Avastin)FDA Link 07/2022 - 05/2014
2	Retinaldehyde (Retinal)IBA 07/2022 - 01/2020
2	pigment epithelium-derived factorIBA 07/2022 - 01/2020
2	cytotropic heterogeneous molecular lipid (CHML)IBA 01/2022 - 11/2021
2	Long Noncoding RNAIBA 12/2021 - 04/2016
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 09/2010
2	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2021 - 09/2020
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2020 - 01/2017
2	Antiviral Agents (Antivirals)IBA 12/2020 - 09/2018
2	Antimalarials (Antimalarial Agents)IBA 12/2020 - 01/2017
2	Brain Natriuretic Peptide (Natrecor)FDA Link 09/2020 - 08/2018
2	TroponinIBA 06/2020 - 06/2015
2	Natriuretic PeptidesIBA 06/2020 - 08/2018
2	Blood Glucose (Blood Sugar)IBA 03/2019 - 01/2017
2	p38 Mitogen-Activated Protein KinasesIBA 03/2019 - 01/2019
2	Tyrosine Kinase InhibitorsIBA 12/2017 - 08/2017
2	ErbB Receptors (EGF Receptor)IBA 12/2017 - 08/2017
2	Pentylenetetrazole (Metrazol)IBA 11/2017 - 08/2015
2	visnaginIBA 02/2016 - 01/2016
2	AnthracyclinesIBA 01/2016 - 05/2011
2	Inosine FDA Link 06/2015 - 01/2011
2	NIMA-Interacting Peptidylprolyl IsomeraseIBA 08/2014 - 09/2013
2	Coloring Agents (Dyes)IBA 06/2014 - 04/2014
2	Sirolimus (Rapamycin)FDA Link 02/2014 - 08/2006
2	Thyroid HormonesIBA 05/2013 - 06/2012

Therapy/Procedure

11	Therapeutics 01/2021 - 05/2012
8	Drug Therapy (Chemotherapy) 01/2022 - 05/2012
3	Lasers (Laser) 10/2021 - 01/2021
3	Photorefractive Keratectomy 02/2020 - 05/2018
2	Radiotherapy 01/2022 - 09/2010
2	Precision Medicine 01/2021 - 09/2020
2	Filtering Surgery 10/2014 - 01/2014
2	Micro-Electrical-Mechanical Systems 07/2012 - 04/2012